Yankees vs. Guardians odds, prediction, line, and time: Proven 2026 MLB pick for June 10
The New York Yankees will try to finish a three-game sweep of the Cleveland Guardians on Wednesday in the finale at Progressive Field. New York has already taken the first two games of the series, winning 7-5 in extra innings on Monday and 3-2 on Tuesday. The Yankees have been one of the league’s hottest teams recently, winning six of their last seven games, while Cleveland enters the matchup looking to avoid being swept at home.
The Yankees are 40-26 on the season, while the Guardians are 37-32. The teams have met five times in 2026, with New York holding a 3-2 edge in the season series. First pitch is scheduled for 1:10 p.m. ET in Cleveland.
On the mound, Cleveland will start Parker Messick, who is 6-2 with a 2.40 ERA. New York will counter with Carlos Rodon, who is 1-2 with a 2.88 ERA. The pitching matchup adds intrigue to a game that could be decided by a narrow margin, especially with both clubs coming in after two low-scoring, competitive contests.
According to the latest betting odds, the Guardians are a slight favorite at -119 on the money line, while the Yankees are listed at -101. The over/under for total runs is set at 7.5, and Cleveland is also listed at -1.5 on the run line at +166.
A projection model that simulates MLB games 10,000 times has identified the over 7.5 runs as its top total recommendation for this matchup. The model notes that five of Cleveland’s last seven games against American League East opponents have gone over the total, and the series opener also finished above the number. It projects strong offensive production from several Yankees hitters, including Cody Bellinger, while Cleveland’s Jose Ramirez is the only Guardian projected to exceed 1.6 total bases.
The model also suggests the game has a higher-than-average chance of producing enough offense to push past the listed total, with its simulations producing an average score of 9.5 combined runs and the over landing 58% of the time. With both teams showing recent scoring ability and the series finale carrying playoff-like urgency, the matchup sets up as an important test for Cleveland and a chance for New York to extend its winning streak.
The game will be available to stream on Fubo.
